open access blog

home J. Otto Lottes Health Sciences Library, Resources and Services Review of stem cells as promising therapy for perianal disease in inflammatory bowel disease: Open Access Blog

Review of stem cells as promising therapy for perianal disease in inflammatory bowel disease: Open Access Blog

By Taira Meadowcroft   Posted in J. Otto Lottes Health Sciences Library Resources and Services
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In August, the physician research team of Dr. Francis Dailey, Dr. Erica Turse, Dr. Maliha Naseer, Dr. Jack Bragg, and Dr. Veysel Tahran published “Review of stem cells as promising therapy for perianal disease in inflammatory bowel disease,” in the open access journal World Journal of Transplantation (WJT).

Launched in 2011, WJT is devoted to reporting the latest research progress and findings in the field of transplantation. The fact the the journal was an open access journal indexed in Pubmed was a big draw to the team. Dr. Tahran says, “if the journal is open access, your papers and ideas can [reach] more people.” For Dr. Dailey, the instant access was the key factor for an open access journal as well. “As a reader of the medical literature I prefer the articles I search for to be open access for ease of obtaining access, and I want others to have this ease as well.”

This review presents current literature of stem cell therapy for patients with perianal inflammatory bowel diseases since the therapy’s emergence in the early 2000s. The team looked at several adipose and bone marrow stem cell studies to analyze the efficacy, outcomes, and safety within those studies. Seeing this as much needed information for their field, the open access journal avenue allowed the team to see their research published sooner rather than later.  “Getting published in this journal was quicker and easier than traditional, subscription-only journals,” mentions Dr. Bragg. Not being a completely print journal gives open access journals the unique ability to review, provide feedback, and publish faster. Open Access journals are able to do this all while still providing quality research.

“There is no difference to me in the manuscript requirements for open access versus other journals. The quality of open access journals is also comparable to that of non-open access journals,” says Dr. Dailey.

If you are interested in publishing in an open access journal, the Health Sciences Library can assist in steering you toward the journals that best fit your research.

Dr. Francis Dailey is a Gastroenterology Fellow at MU Healthcare. He has publishes research related to gastroenterology, inflammatory bowel diseases, clinical gastroenterology, and others. His passion is clinical medicine and gastroenterology, but lovesalso being able to produce clinical research in these fields that can affect everyday clinical practice.

Dr. Jack Bragg is an Associate Professor of Clinical Medicine at MU Healthcare.

Dr. Vesyel Tahran is an Assistant Professor of Clinical Medicine whose research focuses on inflammatory bowel disease, hepatitis, and liver cancer, to name a few. in 2017, he was recognized as a Quality Improvement Champion by the MU Healthcare Department of Medicine’s Quality Improvement Committee  for outstanding work in quality improvement. More recently, Dr. Tahran co-edited the book Viral Hepatitis: Chronic Hepatitis B.

home J. Otto Lottes Health Sciences Library, Resources and Services, Zalk Veterinary Medical Library Effects of therapeutic horseback riding on post-traumatic stress disorder in military veterans: Open Access Blog

Effects of therapeutic horseback riding on post-traumatic stress disorder in military veterans: Open Access Blog

By Taira Meadowcroft   Posted in J. Otto Lottes Health Sciences Library Resources and Services Zalk Veterinary Medical Library
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This month’s open access article features Dr. Rebecca Johnson, PhD, RN, FAAN, FNAP, Professor at the Schools of Nursing and Veterinary Medicine and Director of the Research Center for Human Animal Interaction (ReCHAI). Her research shows that companion animals provide a unique source of social support and facilitate wellness-promoting behaviors. Most recently, she’s been testing the effects on physical activity levels and PTSD of veterans paired with shelter dogs and those participating in therapeutic horseback riding.

Dr. Johnson, and her research team, published in Military Medical Research (MMR) in January 2018. MMR is a completely open access, peer reviewed journal that publishes findings on basic medical science and clinical research related to military medicine. All articles published are made freely and permanently accessible online and all article-processing fees are paid for by the People’s Military Medical Press. It is also indexed by the Directory of Open Access Journals. For more information on the journal, click here.

Effects of therapeutic horseback riding on post-traumatic stress disorder in military veterans focuses on the benefits of a 6-week long therapeutic horseback riding program for veterans diagnosed with PTSD. This randomized trial, with 29 participants, shows that those who participated in the program had statistically significant decreases in PTSD symptoms than those who were part of the controlled group who did not participate in the therapeutic horseback riding. Even those veterans who expressed initial reluctance to participate were found to enjoy the therapy in the end.

home J. Otto Lottes Health Sciences Library, Resources and Services Monitoring undergraduate student needs and activities at Experimental Biology: Open Access Article

Monitoring undergraduate student needs and activities at Experimental Biology: Open Access Article

By Taira Meadowcroft   Posted in J. Otto Lottes Health Sciences Library Resources and Services
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This month’s open access article features Dr. Nicole Nichols, PhD., Assistant Professor in the Department of Biomedical Sciences and an investigator with the Dalton Cardiovascular Research Center. Her research focuses on the central nervous system, specifically the control of breathing in models of motor neuron death.

Dr. Nichols, and her team, chose to use the open access option, which gave them the “ability to provide immediate, open and free access to their work without the standard 12-month embargo that applies to subscription access.” Their article, Monitoring undergraduate student needs and activities at Experimental Biology, was published in the peer-reviewed journal Advances in Physiology Education, which promotes and disseminates educational scholarship in order to enhance teaching and learning of physiology, neuroscience and pathophysiology.

This article was published in conjunction with her responsibilities while serving as the Respiration Section Representative on the American Physiological Society Trainee Advisory Committee. One of the co-authors was also on the committee with her and the other co-author M. Matyas works at the American Physiological Society. Their research “sought to develop and test a pilot survey of undergraduate students to determine how they got involved in research and in presenting at the Experimental Biology (EB) meeting, what they gained from the scientific and career development sessions at the meeting, and how the American Physiological Society (APS) can best support and engage undergraduate students.”

When asked why her team decided to publish in an open access journal, Dr. Nichols said, “we chose to publish this article in the Journal of Advances in Physiology Education because the target audience for this article are Physiology educators. Most physiology educators read this journal and, some, may not have access to non-open access journals.” Dr. Nichols is no stranger to open access avenues, as she had previously published the last piece of her PhD in PLoS One “because the study spanned many different fields and felt that it would be best to publish it in an open access journal.” The instant access to information is the reason why Dr. Nichols would consider publishing in an open access journal again.

home J. Otto Lottes Health Sciences Library Causal relationship between hypoalbuminemia and acute kidney injury (Open Access Article)

Causal relationship between hypoalbuminemia and acute kidney injury (Open Access Article)

By Taira Meadowcroft   Posted in J. Otto Lottes Health Sciences Library
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This week’s open access article features Dr. Wolfgang Widermann, Assistant Professor of Educational, School & Counseling Psychology in the College of Education.His primary research interests include the development of methods for causal inference, methods to determine the direction of effects in nonexperimental studies, and methods for intensive longitudinal data in the person-oriented research setting. He currently serves as an associate editor of Behaviormetrika and the Journal of Person-Oriented Research.

Dr. Widermann, and his research team, published in the World Journal of Nephrology (WJN) in July 2017. WJN is a leading open access journal devoted to reporting the latest, cutting-edge research progress and findings of basic research and clinical practice in the field of nephrology, and is currently indexed in PubMed Central (PMC) and PubMed.

His research in Causal relationship between hypoalbuminemia and acute kidney injury is an update from a meta-analysis in 2010. Since that publication, a large volume of data from clinical studies has been published further evaluating this relationship. This article serves to reevaluate their original hypothesis that hypoalbuminemia is independently associated with increased AKI risk by looking at those newer studies.

 

home J. Otto Lottes Health Sciences Library, Resources and Services A new strategy in neurocritical care nurse continuing stroke education: A hybrid simulation pilot study (Open Access Article)

A new strategy in neurocritical care nurse continuing stroke education: A hybrid simulation pilot study (Open Access Article)

By Taira Meadowcroft   Posted in J. Otto Lottes Health Sciences Library Resources and Services
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The latest article in our open access article series features several University of Missouri faculty and staff:

  1. Robert Bell is a Physician Assistant in neurological surgery and serves as a clinical instructor at the School of Medicine.
  2. Melody Burks is a service line specialist nurse in the neuroscience intensive care unit.
  3. Dr. Premkumar Nattanmai is an assistant professor for clinical neurology, and co-director of the neuroscience intensive care unit.

This research team’s article, A new strategy in noncritical nurse care stroke education: a hybrid simulation pilot study, was published in Electronic Physician in May 2017. Electronic Physician is an open access journal, peer-reviewed journal, that publishes articles in all areas of medical and health sciences. This completely open access journal immediately makes their articles available upon publication, which allows for maximum sharing ability on the new strategy for stroke education this article discusses.

This article discusses a new hybrid simulation approach for education of neurosciences nurses involved in the car of neurocritical care patients. “Simulation creates a learning environment that allows for improving technical and non-technical skills, improving efficiency, practicing rare life-threatening emergencies, and fostering improved attitudes toward teamwork.” This combination of lecture and high-fidelity manikin simulation significantly improved nurses’ understanding and managing of patients in the neuroscience intensive care unit.

Newey, C. R., Bell, R., Burks, M., & Nattanmai, P. (2017). A new strategy in neurocritical care nurse continuing stroke education: A hybrid simulation pilot study. Electronic Physician, 9(5), 4255–4260. http://doi.org/10.19082/4255

home J. Otto Lottes Health Sciences Library, Resources and Services Sodium glucose transporter 2 (SGLT2) inhibition with empagliflozin improves cardiac diastolic function (Open Access Article)

Sodium glucose transporter 2 (SGLT2) inhibition with empagliflozin improves cardiac diastolic function (Open Access Article)

By Taira Meadowcroft   Posted in J. Otto Lottes Health Sciences Library Resources and Services
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This month’s open access article features several University of Missouri School of Medicine Faculty:

  1. Dr. Javad Habibi, PhD., Dr. Annayya Aroor, MD., Dr. Guanghong Jia, PhD., and Dr. Vincent DeMarco, PhD. are all Assistant Research Professors in the department of Endocrinology, Diabetes, and Metabolism.
  2. Dr. Jim Sowers, MD., is a Professor of Medicine, Physiology/Pharmacology, Vice Chair for Research in the Department of Internal Medicine, and Director of the Endocrinology, Diabetes & Metabolism Division. In 2017, Dr. Sowers was awarded the Samual Eichold II Memorial Award for Contributions in Diabetes from the American College of Physicians. The award recognizes those who have made important health care delivery innovations for diabetic patients or research that significantly improves quality of care or clinical management of diabetes.
  3. Dr. R. Scott Rector, PhD., is an Associate Professor in Internal Medicine-Division of Gastroenterology and Hepatology. Dr. Rector’s primary research interests include the role of exercise training, lifestyle modifications, and pharmacological interventions upon oxidative stress and liver metabolism.
  4. Dr. Adam Whaley-Connell, DO., is an Associate Professor of Medicine and Associate Chief of Staff for Research and Development. His research interests include hypertension, and kidney disease.

The research team’s article, Sodium glucose transporter 2 (SGLT2) inhibition with empagliflozin improves cardiac diastolic function in a female rodent model of diabetes was published in Cardiovascular Diabetology in January 2017. Cardiovascular Diabetology is an open access journal that publishes research on all “aspects of the diabetes/cardiovascular interrelationship and the metabolic syndrome; this includes clinical, genetic, experimental, pharmacological, epidemiological and molecular biology research.” With a high impact factor and maxiumum visibilty of articles due to their open access policy, this journal has a wide and global audience.

Here is an excerpt from the abstract:

Obese and diabetic individuals are at increased risk for impairments in diastolic relaxation and heart failure with preserved ejection fraction. The impairments in diastolic relaxation are especially pronounced in obese and diabetic women and predict future cardiovascular disease (CVD) events in this population. Recent clinical data suggest sodium glucose transporter-2 (SGLT2) inhibition reduces CVD events in diabetic individuals, but the mechanisms of this CVD protection are unknown. To determine whether targeting SGLT2 improves diastolic relaxation, we utilized empagliflozin (EMPA) in female db/db mice.

…

In summary, EMPA improved glycemic indices along with diastolic relaxation, as well as SGK1/ENaC profibrosis signaling and associated interstitial fibrosis, all of which occurred in the absence of any changes in BP.

 

home J. Otto Lottes Health Sciences Library, Resources and Services Dr. Loboa: Enhanced cellular infiltration of human adipose-derived stem cells in allograft menisci using a needle-punch method (Open Access Article)

Dr. Loboa: Enhanced cellular infiltration of human adipose-derived stem cells in allograft menisci using a needle-punch method (Open Access Article)

By Taira Meadowcroft   Posted in J. Otto Lottes Health Sciences Library Resources and Services
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This week's open access article features Dr. Elizabeth Loboa, Dean of the College of Engineering, and professor of bioengineering. Her research and techincal focuses are tissue engineering & biomaterials, regenerative medicine and wound healing, and stem cells. Take a look at Dr. Loboa's faculty profile to learn more about her role as the dean, as well as her research. 

Dr. Loboa, with her research team, published in the Journal of Orthopedic Surgery and Research (JOSR) back in October. Journal of Orthopaedic Surgery and Research is an open access, peer-reviewed online journal that encompasses all aspects of clinical and basic research studies related to musculoskeletal issues. JOSR encourages the publication of multidisciplinary research with collaboration amongst clinicians and scientists from different disciplines, which will be the trend in the coming decades. This is why her article is also featured. Dr. Loboa's article is an interdiscplinary collaboration with medicine and engineering. 

Her research in Enhanced cellular infiltration of human adipose-derived stem cells in allograft menisci using a needle-punch method, looked to provide a new method for enhanced cellular infiltration in meniscal allografts. The memiscus is crucial in knee joint function in terms of join stability, and allowing shock absorption, and stress distribution. Their new approach was found to better help better remodel post-surgery, and improve long-term efficacy of meniscal transplantation. 

home J. Otto Lottes Health Sciences Library, Resources and Services Downs and Dalabih: The risk of shorter fasting time for pediatric deep sedation (Open Access Article)

Downs and Dalabih: The risk of shorter fasting time for pediatric deep sedation (Open Access Article)

By Taira Meadowcroft   Posted in J. Otto Lottes Health Sciences Library Resources and Services
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This week's Open Access article features two University of Missouri Faculty. 

  • Dr. Craig Downs, DO., is an Assistant Professor of Clinical Child Health. Dr. Downs primary interest is pediatric critical care. 
  • Dr. Abdallah Dalabih, MD., MBA, is an Assistant Professor of Clinical Child Health. He is involved in clinical research in pediatric critical care and sedatio, with one other study accepted for publication and four others that are in the process of submission. Those four projects will be published by two medical students and two pediatric residents all as first authors. Click here for Dr. Dalabih's faculty profile. 

Dr. Downs, Dr. Dalabih, and their research team published in Anesthesia: Essays and Researches, an open access peer-reviewed international journal by the Pan Arab Federation of Societies of Anesthesiologists. The journal covers technical and clinical studies related to Anesthesia, pain management, intensive care and related topics including ethical and social issues.

Their research in The risk of shorter fasting time for pediatric deep sedation, investigates that safety of a shorter fasting time compared to a longer fasting time before pediatric procedural sedation and analgesia. The current guideline, adopted by the American Academy of Pediatrics, calls for prolonged fasting times. This prospective observational study tries to identify the association between fasting times and complications related to sedation. 

 

Dr. Dalabih took the time to answer some questions we had about open access:

Why did you choose to publish in an Open Access journal?

We selected a journal that is indexed at PubMed so it would be easy to find and that can be accessed all over the world. The journal of Anesthesia: Essays and Researches is an open access journal and is indexed at PubMed with no publication fees, so we elected that journal to showcase our research project.

Would you publish in an Open Access journal again?  If so, why?

Yes, with the increased prices of subscriptions, libraries and physicians are having some difficulty accessing articles they need. This is especially true at countries with poor economies. Open access journals allows those physicians to benefit from the study and will increase the distribution. 

home Cycle of Success, J. Otto Lottes Health Sciences Library, Resources and Services Promoting Open Access Research @ MU

Promoting Open Access Research @ MU

By Taira Meadowcroft   Posted in Cycle of Success J. Otto Lottes Health Sciences Library Resources and Services
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Open Access week is an important week. A week dedicated to highlighting the importance of Open Access and advocating for free, and immediate online access to scholarly research. This year’s theme, “Open in Action,” is all about taking concrete steps to open up research and scholarship and encouraging others to do the same. This was the purpose in creating an open access blog; a way to share research MU faculty choose to publish open access.

Every few weeks, I post about an open access article, right here on our library news page. When typing up the post, I focus on the research itself, the academic accomplishments of the faculty, and the most important, the reasons why they chose to publish in open access. I’ve received several insightul thoughts on why they think open access is important, and to my great delight, all look fantastic as graphics. 😉 Marketing material aside, they are profound thoughts that I hope will strike a chord with other MU faculty, and scholars outside the university, further engaging others and promoting the open access initiative.

 

copy-of-would-you-publish-open-access-again-1why-open-access-social-media-3

 

October 22nd-October 24th, I presented a poster at Merge&Converge’16, the 2016 Mid-Continent Medical Library Association conference. I wanted to show others that promoting open access, and engaging faculty is easier than we think. Faculty can be open access champions.

 

tairamcmlaposter2016

home J. Otto Lottes Health Sciences Library, Resources and Services Facile and Efficient Preparation of Tri-component Fluorescent Glycopolymers (Open Access)

Facile and Efficient Preparation of Tri-component Fluorescent Glycopolymers (Open Access)

By Taira Meadowcroft   Posted in J. Otto Lottes Health Sciences Library Resources and Services
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This week's Open Access article features two University of Missouri Faculty. 

  • Dr. Deborah Chance PhD., is an Assistant Research Professor in the Molecular Microbiology and Immunology Department at the School of Medicine. Dr. Chance's primary research interest is mucins and pathogens in Cystic Fibrosis. If you would like to learn more about Dr. Chance, click here. 
  • Dr. Thomas Mawhinney, PhD., is a Professor in the Department of Biochemistry at the University of Missouri. He is also the State Chemist of Missouri, and the Director of the Agricultural Experiment Station Chemical Laboratories. Click here to learn more about Dr. Mawhinney

Dr. Chance, Dr. Mawhinney, and their research team pubished in JoVE, the Journal of Visualized Experiments. JoVE publishes peer-reviewed scientific video protocols to accelerate biological, medical, chemical and physical research.

This research team chose to pay an additional fee to make Facile and Efficient Preparation of Tri-component Fluorescent Glycopolymers via RAFT-controlled Polymerization open access. Their article/video features "an efficient, three-step synthesis of RAFT-based fluorescent glycopolymers, consisting of glycomonomer preparation, copolymerization, and post-modification, is demonstrated. This protocol can be used to prepare RAFT-based statistical glycopolymers with desired structures." Synthetic glycopolymers are instrumental in various biochemical and biomedical research fields.